72.
(11) Patent number: 2147299
(46) Date of publication: 10.04.2000
(51) Int. Cl.7: C 07 C 279/02, A 61 K 31/675, 31/662, A 61 P 31/02, 31/04
(21) Application number: 98100870/14
(22) Application date: 05.01.1998
(71) Applicant:
Irkutskij institut khimii SO RAN
(72) Inventor:
Lopyrev V.A.,
Antonik L.M.,
Barkova N.P.,
Stankevich V.K.,
Kukharev B.F.
(73) Proprietor:
Irkutskij institut khimii SO RAN
(98) Mail address:
664033, Irkutsk, ul.Favorskogo, d.1, IrIKh SO RAN, patentnyj otde
(54) POLYHEXAMETHYLENE GUANIDINE HYDROXYETHYLENE BIPHOSPHONATE HAVING ANTISEPTIC AND ANTIDOTE PROPERTIES
(57)
FIELD: chemistry and medicine. SUBSTANCE: described is new polyhexamethylene guanidine hydroxyethylene biphosphonate of general formula: wherein n is 4-30, having antiseptic and antidote properties exceeding properties of well known import chlorohexidine bigluconate antiseptic and efficiency. Due to polymeric structure, new antiseptic has low toxicity as compared with well known agents. EFFECT: improved properties of the title compound. 3 ex, 4 tbl
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