1 Scaling-up Ex Vivo Expansion of Mesenchymal Stem/Stromal
Cells for Cellular Therapies ................................. 1
F. Dos Santos, P.Z. Andrade, C.L. da Silva, and
J.M.S. Cabral
2 Mesenchymal Stromal Cell Mechanisms of Immunomodulation
and Homing .................................................. 15
J. Barminko, A. Gray, T. Maguire, R. Schloss, and
M.L. Yarmush
3 Mesenchymal Stem Cell Exosomes: The Future MSC-Based
Therapy? .................................................... 39
Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang,
Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang
Lim
4 The Biology of Mesenchymal Stem Cells in Health and Disease
and Its Relevance to MSC-Based Cell Delivery Therapies ...... 63
Catherine M. Browne, Tung-Liang Chung, and Kerry Atkinson
5 Pulmonary Clinical Applications for Mesenchymal Stem
Cells ....................................................... 87
D. Chambers and R. Hopkins
6 Stem Cell Therapy for Bone Disorders ....................... 101
Elizabeth Rosado Balmayor, and Martijn van Griensven
7 Mesenchymal Stem Cell Therapies for Bone and Tendon
Conditions ................................................. 117
Mark Young and Michael R. Doran
8 Mesenchymal Stromal Cells and the Repair of Cartilage
Tissue ..................................................... 145
Michael R. Doran and Mark Young
9 Mesenchymal Stem Cells and Haematopoietic Stem Cell
Culture .................................................... 161
Matthew M. Cook
10 Mesenchymal Stem Cells for Treatment and Prevention of
Graft-Versus-Host Disease and Graft Failure After
Hematopoietic Stem Cell Transplantation and Future
Challenges ................................................. 173
Olle Ringdén
11 Mesenchymal Stromal Cell Therapy in Crohn's Disease ........ 207
Ilse Molendijk, Daan W. Hommes, and Marjolijn Duijvestein
12 Application of Mesenchymal Stem Cells in Amyotrophic
Lateral Sclerosis .......................................... 217
Josep Gamez
13 Mesenchymal Stem Cell Therapy for Heart Disease ............ 241
Massimiliano Gnecchi and Elisabetta Cervio
14 Advances in Lentiviral Vector-based Cell Therapy
with Mesenchymal Stem Cells ................................ 271
Lajos Baranyi and Boro Dropulic
15 Genetically Engineered Mesenchymal Stem Cells for Cell
and Gene Therapy ........................................... 321
Yunjoon Jung and Jan A. Nolta
16 Optimal Tissue Sources of Mesenchymal Stromal Cells
for Clinical Applications .................................. 355
Celena Heazlewood and Kerry Atkinson
17 Regulatory Considerations Applicable to Manufacturing
of Human Placenta-Derived Mesenchymal Stromal Cells (MSC)
Used in Clinical Trials in Australia and Comparison to USA
and European Regulatory Frameworks .......................... 373
Nina Ilic, Dalia Khalil, Sonia Hancock, and Kerry Atkinson
18 Mesenchymal Stem Cell Therapy for Peripheral Vascular
Diseases .................................................... 405
Anjan K. Das, Pawan K. Gupta, C.H. Anoop, Sudha
Balasubramanian, and Anish S. Majumdar
19 Mesenchymal Stromal Cells in the Clinic: What Do the
Clinical Trials Say? ........................................ 423
Vivek Tanavde and Mohan C. Vemuri
About the Editors .............................................. 435
Index .......................................................... 437
|
