Protein targeting with small molecules: chemical biology techniques and applications / ed. by H.Osada. - Hoboken: Wiley, 2009. - ix, 289 p., [8] p. of plates: ill. - Incl. bibl. ref. - Ind.: p.277-289. - ISBN 978-0-470-12053-8  Место хранения:   056 | Институт химической биологии и фундаментальной медицины CO РАН | Новосибирск| Библиотека

Оглавление / Contents

Contributors .................................................. vii Preface ........................................................ ix 1 Chemical Biology Based on Small Molecule—Protein Interaction .................................................. 1 Hiroyuki Osada 2 Target Profiling of Small Molecules ......................... 11 Leonid L. Chepelev and Michel Dumontier 3 Novel Applications of Affinity Beads ........................ 39 Yasuaki Kabe, Mamoru Hatakeyama, Satoshi Sakamoto, Kosuke Nishio, and Hiroshi Handa 4 Recent Developments and Advances in Chemical Arrays ......... 57 Naoki Kanoh and Hiroyuki Osada 5 Use of the Phage Display Technique to Identify the Target Protein ..................................................... 81 Yoon Sun Cho and Ho Jeong Kwon 6 Development of Fluorescent Probes for Small Molecules ....... 91 Adrian P. Neal and Carsten Schultz 7 Development of Small-Molecule Ligands and Inhibitors ....... 115 Leonid L. Chepelev, Nikolai L. Chepelev, Hooman Shadnia, William G. Willmore, James S. Wright, and Michel Dumontier 8 Interaction of a Biological Response Modifier with Proteins ................................................... 149 Yuichi Hashimoto 9 Chemical Biology of Cell Motility Inhibitors ............... 169 Tatsuro Kawamura, Mitsuhiro Kitagawa, and Masaya Imoto 10 Chemical Biology of Cell Surface Oligosaccharides .......... 189 Prabhani U. Atukorale, Sean S. Choi, Udayanath Aich, Christopher T. Campbell, M. Adam Meledeo, and Kevin J. Yarema 11 Chemical Genomics Based on Yeast Genetics .................. 223 Shinichi Nishimura, Yoko Yashiroda, and Minoru Yoshida 12 Data on Small Molecules and Their Target Proteins .......... 239 Takeo Usui, Akiko Saito, and Hiroyuki Osada Index ......................................................... 277