Preface and Dedication to Christian R.H. Raetz
JoAnne Stubbe ............................................... xi
Prefatories
A Mitochondrial Odyssey
Walter Neupert ............................................... 1
The Fires of Life
Gottfried Schatz ............................................ 34
Chromatin, Epigenetics, and Transcription Theme
Introduction to Theme "Chromatin, Epigenetics, and
Transcription"
Joan W. Conaway ............................................. 61
The COMPASS Family of Histone H3K4 Methylases: Mechanisms of
Regulation in Development and Disease Pathogenesis
Ali Shilatifard ............................................. 65
Programming of DNA Methylation Patterns
Howard Cedar and Yehudit Bergman ............................ 97
RNA Polymerase II Elongation Control
Qiang Zhou, Tiandao Li, and David H. Price ................. 119
Genome Regulation by Long Noncoding RNAs
John L. Rinn and Howard Y. Chang ........................... 145
Protein Tagging Theme
The Ubiquitin System, an Immense Realm
Alexander Varshavsky ....................................... 167
Ubiquitin and Proteasomes in Transcription
Fuqiang Geng, Sabine Wenzel, and William P. Tansey ......... 177
The Ubiquitin Code
David Komander and Michael Rape ............................ 203
Ubiquitin and Membrane Protein Turnover: From Cradle to
Grave
Jason A. MacGurn, Pi-Chiang Hsu, and Scott D. Emr .......... 231
The N-End Rule Pathway
Takafumi Tasaki, Shashikanth M. Sriram, Kyong Soo Park,
and Yong Tae Kwon .......................................... 261
Ubiquitin-Binding Proteins: Decoders of Ubiquitin-Mediated
Cellular Functions
Koraljka Husnjak and Ivan Dikic ............................ 291
Ubiquitin-Like Proteins
Annemarthe G. van der Veen and Hidde L. Ploegh ............. 323
Recent Advances in Biochemistry
Toward the Single-Hour High-Quality Genome
Patrik L. Ståhl and Joakim Lundeberg ....................... 359
Mass Spectrometry-Based Proteomics and Network Biology
Ariel Bensimon, Albert J.R. Heck, and Ruedi Aebersold ...... 379
Membrane Fission: The Biogenesis of Transport Carriers
Felix Campelo and Vivek Malhotra ........................... 407
Emerging Paradigms for Complex Iron-Sulfur Cofactor
Assembly and Insertion
John W. Peters and Joan B. Broderick ....................... 429
Structural Perspective of Peptidoglycan Biosynthesis and
Assembly
Andrew L. Levering, Susan S. Safadi, and Natalie
C.J. Strynadka ............................................. 451
Discovery, Biosynthesis, and Engineering of Lantipeptides
Patrick J. Knerr and Wilfred A. van der Donk ............... 479
Regulation of Glucose Transporter Translocation in Health
and Diabetes
Jonathan S. Bogan .......................................... 507
Structure and Regulation of Soluble Guanylate Cyclase
Emily R. Derbyshire and Michael A. Marletta ................ 533
The MPS1 Family of Protein Kinases
Xuedong Liu and Mark Winey ................................. 561
The Structural Basis for Control of Eukaryotic Protein
Kinases
Jane A. Endicott, Martin E.M. Noble, and Louise
N. Johnson ................................................. 587
Measurements and Implications of the Membrane Dipole
Potential
Liguo Wang ................................................. 615
GTPase Networks in Membrane Traffic
Emi Mizuno-Yamasaki, Felix Rivera-Molina, and Peter
Novick ..................................................... 637
Roles for Actin Assembly in Endocytosis
Olivia L. Mooren, Brian J. Galletta, and John A. Cooper .... 661
Lipid Droplets and Cellular Lipid Metabolism
Tobias C. Walther and Robert V. Farese jr. ................. 687
Adipogenesis: From Stem Cell to Adipocyte
Qi Qun Tang and M. Daniel Lane ............................. 715
Pluripotency and Nuclear Reprogramming
Marion Dejosez and Thomas P. Zwaka ......................... 737
Endoplasmic Reticulum Stress and Type 2 Diabetes
Sung Hoon Back and Randal J. Kaufman ....................... 767
Structure Unifies the Viral Universe
Nicola G.A. Abrescia, Dennis H. Bamford, Jonathan
M. Grimes, and David I. Stuart ............................. 795
Indexes
Cumulative Index of Contributing Authors, Volumes 77-81 ....... 823
Cumulative Index of Chapter Titles, Volumes 77-81 ............. 827
Errata
An online log of corrections to Annual Review of
Biochemistry articles may be found at
http://biochem.annualreviews.org/errata.shtml
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