Preface ........................................................ ix
Chapter 1 Genetic and Epigenetic Regulation of
Transgenerational Changes in Genome Stability: An
Overview ............................................. 1
Olga Kovalchuk and Igor Kovalchuk
Chapter 2 Genetic and Epigenetic Mechanisms Ensuring
Stability of Mammalian Genomes ....................... 7
Jody Filkowski and Olga Kovalchuk
Chapter 3 Genetic and Epigenetic Regulation of Genome
Stability in Plants ................................. 33
Alex Boyko and Igor Kovalchuk
Chapter 4 Evolution of the Fpg/Nei Family of DNA
Glycosylases ........................................ 71
Dorothy E. Pumo, Ramiro Barrantes-Reynolds, Scott
Kathe, Susan S. Wallace and Jeffrey P. Bond
Chapter 5 Stress-Induced Mutagenesis in Bacteria .............. 89
Audrey Golubov
Chapter 6 Clustered Regularly Interspaced Short Palindromic
Repeats (CRISPR) Loci as an Example of Bacterial
Adaptive Immunity Against Phages ................... 105
Igor Kovalchuk and Andrey Golubov
Chapter 7 White Tail Tip Inheritance in Mice: From the "Kit
Locus" to a New Mode of Heredity ................... 113
Minoo Rassoulzadegan
Chapter 8 Role of Epigenetic Changes in the Non-Targeted
Radiation-Induced Effects: Understanding the
Epigenetics of Bystander and Transgenerational
Effects ............................................ 131
Jody Filkowski, Yaroslav Ilnytsky and Olga
Kovalchuk
Chapter 9 A Review of Tandem Repeat Sequences: Markers of
Genetic Instability ................................ 151
Carole Yauk and John D.H. Stead
Chapter 10 Transgenerational Genomic Instability in Fish ...... 169
Carmel Mothersill and Colin Seymour
Chapter 11 Germ Cell-Mediated Mutagenesis: Insights from the
λ Transgenic Medaka ................................ 199
Richard N. Winn
Chapter 12 Transgenerational Genomic Instability in Mammals ... 225
Carmel Mothersill and Colin Seymour
Chapter 13 The Epigenetic (Re)Programming of Phenotypic
Differences in Behavior ............................ 263
Patrick O. McGowan, Michael J. Meaney and
Moshe Szyf
Chapter 14 Lifestyle Factors, Epigenetic Abnormalities, and
Genomic Instability: Implications for
Carcinogenesis ..................................... 291
Igor P. Pogribny
Chapter 15 Paramutations in Plants ............................ 309
Palak Kathiria and Igor Kovalchuk
Chapter 16 Transgenerational Response to Stress in Plants
Involves Genome Destabilization, Changes in
Methylation and Increase in Stress Tolerance ....... 321
Igor Kovalchuk, Palak Kathiria and Alex Boyko
Chapter 17 Plant Transposable Elements and Plasticity of
Host Genomes: The Stress Connection ................ 343
Marie-Angèle Grandbastien
Chapter 18 Intra- and Interplant Stress Signalling:
Bystander-Like Effects Found in Plants ............. 377
Franz J. Zemp
Chapter 19 Systemic Heuristic Approaches Guide the
Interaction of Enhanced Genetic Diversity and
Complex Stresses to Generate Better Wheat
Germplasm Faster and at Lower Cost ................. 401
A. Comeau, V.R. Caetano, S. Haber, F. Langevin,
M. Lévesque and J. Gilbert
Index ......................................................... 447
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